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Interleukin-17a Induces Neuronal Differentiation of Induced-Pluripotent Stem Cell-Derived Neural Progenitors From Autistic and Control Subjects

Prenatal exposure to maternal immune activation (MIA) has been suggested to increase the probability of autism spectrum disorder (ASD). Recent evidence from animal studies indicates a key role for interleukin-17a (IL-17a) in promoting MIA-induced behavioral and brain abnormalities reminiscent of ASD...

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Detalles Bibliográficos
Autores principales: Gomes, Ana Karolyne Santos, Dantas, Rafaelly Mayara, Yokota, Bruno Yukio, Silva, André Luiz Teles e, Griesi-Oliveira, Karina, Passos-Bueno, Maria Rita, Sertié, Andréa Laurato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964130/
https://www.ncbi.nlm.nih.gov/pubmed/35360153
http://dx.doi.org/10.3389/fnins.2022.828646