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Casual Associations and Shape Between Prepuberty Body Mass Index and Early Onset of Puberty: A Mendelian Randomization and Dose–Response Relationship Analysis

BACKGROUND: There is an ongoing controversial issue regarding whether onset of puberty is related to childhood BMI. OBJECTIVES: This study aims at investigating the causal association and its shape between prepuberty BMI and early puberty onset. METHODS: Breast development and testicular volume were...

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Detalles Bibliográficos
Autores principales: Fang, Jiao, Yuan, Jingyi, Zhang, Dandan, Liu, Wanxu, Su, Puyu, Wan, Yuhui, Zhang, Zhihua, Tao, Fangbiao, Sun, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964141/
https://www.ncbi.nlm.nih.gov/pubmed/35360058
http://dx.doi.org/10.3389/fendo.2022.853494