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Computational Repurposing of Drugs and Natural Products Against SARS-CoV-2 Main Protease (M(pro)) as Potential COVID-19 Therapies

We urgently need to identify drugs to treat patients suffering from COVID-19 infection. Drugs rarely act at single molecular targets. Off-target effects are responsible for undesirable side effects and beneficial synergy between targets for specific illnesses. They have provided blockbuster drugs, e...

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Detalles Bibliográficos
Autores principales: Piplani, Sakshi, Singh, Puneet, Petrovsky, Nikolai, Winkler, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964187/
https://www.ncbi.nlm.nih.gov/pubmed/35359601
http://dx.doi.org/10.3389/fmolb.2022.781039