Rhein Ameliorates Cognitive Impairment in an APP/PS1 Transgenic Mouse Model of Alzheimer's Disease by Relieving Oxidative Stress through Activating the SIRT1/PGC-1α Pathway

Mitochondrial oxidative stress plays an important role in the pathogenesis of Alzheimer's disease (AD). Recently, antioxidant therapy has been considered an effective strategy for the treatment of AD. Our previous work discovered that rhein relieved mitochondrial oxidative stress in β-amyloid (...

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Detalles Bibliográficos
Autores principales: Yin, Zhihui, Gao, Demin, Du, Ke, Han, Chen, Liu, Yuhan, Wang, Ying, Gao, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964225/
https://www.ncbi.nlm.nih.gov/pubmed/35360200
http://dx.doi.org/10.1155/2022/2524832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964225/
https://www.ncbi.nlm.nih.gov/pubmed/35360200
http://dx.doi.org/10.1155/2022/2524832

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