An Effective Sodium-Dependent Glucose Transporter 2 Inhibition, Canagliflozin, Prevents Development of Hypertensive Heart Failure in Dahl Salt-Sensitive Rats

Background: The aim of the study was to investigate the protective effect of canagliflozin (CANA) on myocardial metabolism and heart under stress overload and to further explore its possible molecular mechanism. Methods: High-salt diet was used to induce heart failure with preserved ejection fractio...

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Detalles Bibliográficos
Autores principales: He, Lili, Ma, Sai, Zuo, Qingjuan, Zhang, Guorui, Wang, Zhongli, Zhang, Tingting, Zhai, Jianlong, Guo, Yifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964360/
https://www.ncbi.nlm.nih.gov/pubmed/35370704
http://dx.doi.org/10.3389/fphar.2022.856386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964360/
https://www.ncbi.nlm.nih.gov/pubmed/35370704
http://dx.doi.org/10.3389/fphar.2022.856386

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