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An Effective Sodium-Dependent Glucose Transporter 2 Inhibition, Canagliflozin, Prevents Development of Hypertensive Heart Failure in Dahl Salt-Sensitive Rats
Background: The aim of the study was to investigate the protective effect of canagliflozin (CANA) on myocardial metabolism and heart under stress overload and to further explore its possible molecular mechanism. Methods: High-salt diet was used to induce heart failure with preserved ejection fractio...
Autores principales: | He, Lili, Ma, Sai, Zuo, Qingjuan, Zhang, Guorui, Wang, Zhongli, Zhang, Tingting, Zhai, Jianlong, Guo, Yifang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964360/ https://www.ncbi.nlm.nih.gov/pubmed/35370704 http://dx.doi.org/10.3389/fphar.2022.856386 |
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