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Switching to the cyclic pentose phosphate pathway powers the oxidative burst in activated neutrophils

Neutrophils are cells at the frontline of innate immunity that can quickly activate effector functions to eliminate pathogens upon stimulation. However, little is known about the metabolic adaptations that power these functions. Here we show rapid metabolic alterations in neutrophils upon activation...

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Detalles Bibliográficos
Autores principales: Britt, Emily C., Lika, Jorgo, Giese, Morgan A., Schoen, Taylor J., Seim, Gretchen L., Huang, Zhengping, Lee, Pui Y., Huttenlocher, Anna, Fan, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964420/
https://www.ncbi.nlm.nih.gov/pubmed/35347316
http://dx.doi.org/10.1038/s42255-022-00550-8