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Increased CDCA2 Level Was Related to Poor Prognosis in Hepatocellular Carcinoma and Associated With Up-Regulation of Immune Checkpoints

BACKGROUND: Cell division cycle-associated protein 2 (CDCA2) is a member of cell cycle-related proteins. CDCA2 plays a role in the regulation of protein phosphatase 1(PP1) γ-dependent DNA damage response (DDR) and H3 phosphorylation. CDCA2 promotes the tumorigenesis and development of several types...

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Detalles Bibliográficos
Autores principales: Tang, Mengying, Liao, Mingchu, Ai, Xiaohong, He, Guicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964461/
https://www.ncbi.nlm.nih.gov/pubmed/35372372
http://dx.doi.org/10.3389/fmed.2021.773724