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Melatonin Maintains Inner Blood–Retinal Barrier by Regulating Microglia via Inhibition of PI3K/Akt/Stat3/NF-κB Signaling Pathways in Experimental Diabetic Retinopathy

Microglial activation and melatonin protection have been reported in diabetic retinopathy (DR). Whether melatonin could regulate microglia to protect the inner blood–retinal barrier (iBRB) remains unknown. In this study, the role of microglia in iBRB breakdown and the mechanisms of melatonin’s regul...

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Detalles Bibliográficos
Autores principales: Tang, Lei, Zhang, Chaoyang, Lu, Lixia, Tian, Haibin, Liu, Kun, Luo, Dawei, Qiu, Qinghua, Xu, Guo-Tong, Zhang, Jingfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964465/
https://www.ncbi.nlm.nih.gov/pubmed/35371022
http://dx.doi.org/10.3389/fimmu.2022.831660