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Double-Negative T Cells Regulate Hepatic Stellate Cell Activation to Promote Liver Fibrosis Progression via NLRP3

AIM: We mainly explored the role and mechanism of double-negative T cells (DNTs) in liver fibrosis. METHODS: DNTs were co-cultured with mouse hepatic stellate cells (HSCs). Later, cell viability was detected by Cell Counting Kit-8 (CCK-8) assay; α-SMA expression was measured through fluorescence sta...

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Detalles Bibliográficos
Autores principales: Yang, Yi, Sheng, Yongjia, Wang, Jin, Zhou, Xiaohong, Li, Wenyan, Zhang, Caiqun, Guo, Li, Han, Chenyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964496/
https://www.ncbi.nlm.nih.gov/pubmed/35371052
http://dx.doi.org/10.3389/fimmu.2022.857116