DNA methylation maintenance at the p53 locus initiates biliary-mediated liver regeneration

In cases of extensive liver injury, biliary epithelial cells (BECs) dedifferentiate into bipotential progenitor cells (BPPCs), then redifferentiate into hepatocytes and BECs to accomplish liver regeneration. Whether epigenetic regulations, particularly DNA methylation maintenance enzymes, play a rol...

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Detalles Bibliográficos
Autores principales: He, Jianbo, Zhou, Yang, Qian, Chuanfang, Wang, Danyang, Yang, Zhuolin, Huang, Zhuofu, Sun, Junhui, Ni, Rui, Yang, Qifen, Chen, Jingying, Luo, Lingfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964678/
https://www.ncbi.nlm.nih.gov/pubmed/35351894
http://dx.doi.org/10.1038/s41536-022-00217-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964678/
https://www.ncbi.nlm.nih.gov/pubmed/35351894
http://dx.doi.org/10.1038/s41536-022-00217-8

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