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Förster resonance energy transfer biosensors for fluorescence and time-gated luminescence analysis of rac1 activity

Genetically encoded, Förster resonance energy transfer (FRET) biosensors enable live-cell optical imaging of signaling molecules. Small conformational changes often limit the dynamic range of biosensors that combine fluorescent proteins (FPs) and sensing domains into a single polypeptide. To address...

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Detalles Bibliográficos
Autores principales: Pham, Ha, Hoseini Soflaee, Mona, Karginov, Andrei V., Miller, Lawrence W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964680/
https://www.ncbi.nlm.nih.gov/pubmed/35351946
http://dx.doi.org/10.1038/s41598-022-09364-w