Structural and biochemical characterization of in vivo assembled Lactococcus lactis CRISPR-Csm complex

The small RNA-mediated immunity in bacteria depends on foreign RNA-activated and self RNA-inhibited enzymatic activities. The multi-subunit Type III-A CRISPR-Cas effector complex (Csm) exemplifies this principle and is in addition regulated by cellular metabolites such as divalent metals and ATP. Re...

Descripción completa

Detalles Bibliográficos
Autores principales: Sridhara, Sagar, Rai, Jay, Whyms, Charlisa, Goswami, Hemant, He, Huan, Woodside, Walter, Terns, Michael P., Li, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964682/
https://www.ncbi.nlm.nih.gov/pubmed/35351985
http://dx.doi.org/10.1038/s42003-022-03187-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964682/
https://www.ncbi.nlm.nih.gov/pubmed/35351985
http://dx.doi.org/10.1038/s42003-022-03187-1

Ejemplares similares