Cargando…
Structural and biochemical characterization of in vivo assembled Lactococcus lactis CRISPR-Csm complex
The small RNA-mediated immunity in bacteria depends on foreign RNA-activated and self RNA-inhibited enzymatic activities. The multi-subunit Type III-A CRISPR-Cas effector complex (Csm) exemplifies this principle and is in addition regulated by cellular metabolites such as divalent metals and ATP. Re...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964682/ https://www.ncbi.nlm.nih.gov/pubmed/35351985 http://dx.doi.org/10.1038/s42003-022-03187-1 |