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Activated endothelial cells induce a distinct type of astrocytic reactivity

Reactive astrogliosis is a universal response of astrocytes to abnormal events and injuries. Studies have shown that proinflammatory microglia can polarize astrocytes (designated A1 astrocytes) toward a neurotoxic phenotype characterized by increased Complement Component 3 (C3) expression. It is sti...

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Detalles Bibliográficos
Autores principales: Taylor, Xavier, Cisternas, Pablo, Jury, Nur, Martinez, Pablo, Huang, Xiaoqing, You, Yanwen, Redding-Ochoa, Javier, Vidal, Ruben, Zhang, Jie, Troncoso, Juan, Lasagna-Reeves, Cristian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964703/
https://www.ncbi.nlm.nih.gov/pubmed/35351973
http://dx.doi.org/10.1038/s42003-022-03237-8