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APOE-ε4 modulates the association among plasma Aβ(42)/Aβ(40), vascular diseases, neurodegeneration and cognitive decline in non-demented elderly adults
Including apolipoprotein E-ε4 (APOE-ε4) status and older age into consideration may increase the accuracy of plasma Aβ(42)/Aβ(40) detecting Aβ+ individuals, but the rationale behind this remains to be fully understood. Besides, both Aβ pathology and vascular diseases are related to neurodegeneration...
Autores principales: | Shi, Dai, Xie, Siwei, Li, Anqi, Wang, Qingyong, Guo, Hongbo, Han, Ying, Xu, Huaxi, Gan, Wen-Biao, Zhang, Lei, Guo, Tengfei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964707/ https://www.ncbi.nlm.nih.gov/pubmed/35351867 http://dx.doi.org/10.1038/s41398-022-01899-w |
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