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Acox2 is a regulator of lysine crotonylation that mediates hepatic metabolic homeostasis in mice

Acyl-CoA oxidase 2 (Acox2) is an enzyme involved in peroxisomal bile acid synthesis and branched-chain fatty acid degradation. Acox2 knockout (−/−) mice spontaneously developed liver cancer with marked lymphocytic infiltrate. Tandem-affinity purification coupled with mass spectrometry analysis revea...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Chen, Yuling, Zhang, Zhao, Tao, Xiang, Xu, Sha, Zhang, Xinyan, Zurashvili, Tinatin, Lu, Zhouping, Bayascas, José Ramon, Jin, Liping, Zhao, Jianyuan, Zhou, Xiangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964741/
https://www.ncbi.nlm.nih.gov/pubmed/35351852
http://dx.doi.org/10.1038/s41419-022-04725-9