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In vitro ballooned hepatocytes can be produced by primary human hepatocytes and hepatic stellate cell sheets

Despite the increasing prevalence of Nonalcoholic steatohepatitis (NASH) worldwide, there is no effective treatment available for this disease. “Ballooned hepatocyte” is a characteristic finding in NASH and is correlated with disease prognosis, but their mechanisms of action are poorly understood; f...

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Detalles Bibliográficos
Autores principales: Hasui, Nobuhiro, Sakaguchi, Katsuhisa, Ogawa, Tetsuya, Sakamoto, Yoshihiro, Shimizu, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964766/
https://www.ncbi.nlm.nih.gov/pubmed/35351975
http://dx.doi.org/10.1038/s41598-022-09428-x