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Different Spatial and Temporal Roles of Monocytes and Monocyte-Derived Cells in the Pathogenesis of an Imiquimod Induced Lupus Model

Mounting evidence indicates the importance of aberrant Toll-like receptor 7 (TLR7) signaling in the pathogenesis of systemic lupus erythematosus (SLE). However, the mechanism of disease progression remains unclear. An imiquimod (IMQ)-induced lupus model was used to analyze the lupus mechanism relate...

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Detalles Bibliográficos
Autores principales: Nomura, Atsushi, Mizuno, Miho, Noto, Daisuke, Aoyama, Aki, Kuga, Taiga, Murayama, Goh, Chiba, Asako, Miyake, Sachiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964788/
https://www.ncbi.nlm.nih.gov/pubmed/35371102
http://dx.doi.org/10.3389/fimmu.2022.764557