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Inhibition of triple negative breast cancer-associated inflammation, tumor growth and brain colonization by targeting monoacylglycerol lipase

While the prevalence of breast cancer metastasis in the brain is significantly higher in triple negative breast cancers (TNBCs), there is a lack of novel and/or improved therapies for these patients. Monoacylglycerol lipase (MAGL) is a hydrolase involved in lipid metabolism that catalyzes the degrad...

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Detalles Bibliográficos
Autores principales: Benchama, Othman, Tyukhtenko, Sergiy, Malamas, Michael S., Williams, Mark K., Makriyannis, Alexandros, Avraham, Hava Karsenty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964799/
https://www.ncbi.nlm.nih.gov/pubmed/35351947
http://dx.doi.org/10.1038/s41598-022-09358-8