Adiponectin receptor agonist ameliorates cardiac lipotoxicity via enhancing ceramide metabolism in type 2 diabetic mice

Accumulation of lipids and their metabolites induces lipotoxicity in diabetic cardiomyopathy. Lowering ceramide concentration could reduce the impact of metabolic damage to target organs. Adiponectin improves lipotoxicity through its receptors (AdiopRs), which have sequence homology with ceramidase...

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Detalles Bibliográficos
Autores principales: Kim, Yaeni, Lim, Ji Hee, Kim, Eun Nim, Hong, Yu Ah, Park, Hun-Jun, Chung, Sungjin, Choi, Bum Soon, Kim, Yong-Soo, Park, Ji Yong, Kim, Hye Won, Park, Cheol Whee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964809/
https://www.ncbi.nlm.nih.gov/pubmed/35351872
http://dx.doi.org/10.1038/s41419-022-04726-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964809/
https://www.ncbi.nlm.nih.gov/pubmed/35351872
http://dx.doi.org/10.1038/s41419-022-04726-8

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