Effect of Leflunomide on Pegloticase Response Rate in Patients with Uncontrolled Gout: A Retrospective Study

BACKGROUND: Pegloticase, a PEGylated uricase for uncontrolled gout, rapidly lowers serum urate (SU). Not all patients complete a full-therapy course because anti-pegloticase antibodies can develop, causing efficacy loss and infusion reactions. The literature and clinical trial data indicate that met...

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Detalles Bibliográficos
Autores principales: Masri, Karim Richard, Padnick-Silver, Lissa, Winterling, Kevin, LaMoreaux, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964845/
https://www.ncbi.nlm.nih.gov/pubmed/34997911
http://dx.doi.org/10.1007/s40744-021-00421-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964845/
https://www.ncbi.nlm.nih.gov/pubmed/34997911
http://dx.doi.org/10.1007/s40744-021-00421-w

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