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The Metalloprotease-Disintegrin ADAM8 Alters the Tumor Suppressor miR-181a-5p Expression Profile in Glioblastoma Thereby Contributing to Its Aggressiveness

Glioblastoma (GBM) as the most common and aggressive brain tumor is characterized by genetic heterogeneity, invasiveness, radio-/chemoresistance, and occurrence of GBM stem-like cells. The metalloprotease-disintegrin ADAM8 is highly expressed in GBM tumor and immune cells and correlates with poor su...

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Detalles Bibliográficos
Autores principales: Schäfer, Agnes, Evers, Lara, Meier, Lara, Schlomann, Uwe, Bopp, Miriam H. A., Dreizner, Gian-Luca, Lassmann, Olivia, Ben Bacha, Aaron, Benescu, Andreea-Cristina, Pojskic, Mirza, Preußer, Christian, von Strandmann, Elke Pogge, Carl, Barbara, Nimsky, Christopher, Bartsch, Jörg W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964949/
https://www.ncbi.nlm.nih.gov/pubmed/35371977
http://dx.doi.org/10.3389/fonc.2022.826273