Robust genome and RNA editing via CRISPR nucleases in PiggyBac systems

CRISPR/Cas-mediated genome editing in human pluripotent stem cells (hPSCs) offers unprecedented opportunities for developing in vitro disease modeling, drug screening and cell-based therapies. To efficiently deliver the CRISPR components, here we developed two all-in-one vectors containing Cas9/gRNA...

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Detalles Bibliográficos
Autores principales: Jiang, Yuqian, Hoenisch, Rachel Catherine, Chang, Yun, Bao, Xiaoping, Cameron, Craig E., Lian, Xiaojun Lance
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964983/
https://www.ncbi.nlm.nih.gov/pubmed/35386818
http://dx.doi.org/10.1016/j.bioactmat.2022.01.046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964983/
https://www.ncbi.nlm.nih.gov/pubmed/35386818
http://dx.doi.org/10.1016/j.bioactmat.2022.01.046

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