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pH-Responsive Hyaluronic Acid Nanoparticles for Enhanced Triple Negative Breast Cancer Therapy

PURPOSE: This study emphasized that dasatinib (DAS) and olaparib (OLA) have synergistic effects on triple negative breast cancer, by inducing DNA damage and inhibiting DNA damage repair. However, poor water solubility, short half-life of drugs, and low drug concentration in tumor tissue limit the cl...

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Detalles Bibliográficos
Autores principales: Zeng, Xiangle, Wang, Hairong, Zhang, Yawen, Xu, Xue, Yuan, Xinyi, Li, Jianchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965017/
https://www.ncbi.nlm.nih.gov/pubmed/35369031
http://dx.doi.org/10.2147/IJN.S360500