The Small GTPase RHOA Links SLP65 Activation to PTEN Function in Pre B Cells and Is Essential for the Generation and Survival of Normal and Malignant B Cells

The generation, differentiation, survival and activation of B cells are coordinated by signals emerging from the B cell antigen receptor (BCR) or its precursor, the pre-BCR. The adaptor protein SLP65 (also known as BLNK) is an important signaling factor that controls pre-B cell differentiation by do...

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Detalles Bibliográficos
Autores principales: Vadakumchery, Anila, Faraidun, Hemin, Ayoubi, Omar El, Outaleb, Issame, Schmid, Vera, Abdelrasoul, Hend, Amendt, Timm, Khadour, Ahmad, Setz, Corinna, Göhring, Katharina, Lodd, Karoline, Hitzing, Christoffer, Alkhatib, Alabbas, Bilal, Mayas, Benckendorff, Julian, Al Shugri, Abdul Kader, Brakebusch, Cord Herbert, Engels, Niklas, Datta, Moumita, Hobeika, Elias, Alsadeq, Ameera, Jumaa, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965026/
https://www.ncbi.nlm.nih.gov/pubmed/35371049
http://dx.doi.org/10.3389/fimmu.2022.842340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965026/
https://www.ncbi.nlm.nih.gov/pubmed/35371049
http://dx.doi.org/10.3389/fimmu.2022.842340

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