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Macrophage-targeting gene silencing orchestrates myocardial microenvironment remodeling toward the anti-inflammatory treatment of ischemia-reperfusion (IR) injury

Ischemia-reperfusion (IR) injury represents a major cause of myocardial dysfunction after infarction and thrombolytic therapy, and it is closely related to the free radical explosion and overwhelming inflammatory responses. Herein, macrophage-targeting nanocomplexes (NCs) are developed to mediate ef...

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Detalles Bibliográficos
Autores principales: Wang, Yao, Hou, Mengying, Duan, Shanzhou, Zhao, Ziyin, Wu, Xuejie, Chen, Yongbing, Yin, Lichen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965030/
https://www.ncbi.nlm.nih.gov/pubmed/35386446
http://dx.doi.org/10.1016/j.bioactmat.2022.01.026