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Macrophage-targeting gene silencing orchestrates myocardial microenvironment remodeling toward the anti-inflammatory treatment of ischemia-reperfusion (IR) injury
Ischemia-reperfusion (IR) injury represents a major cause of myocardial dysfunction after infarction and thrombolytic therapy, and it is closely related to the free radical explosion and overwhelming inflammatory responses. Herein, macrophage-targeting nanocomplexes (NCs) are developed to mediate ef...
Autores principales: | Wang, Yao, Hou, Mengying, Duan, Shanzhou, Zhao, Ziyin, Wu, Xuejie, Chen, Yongbing, Yin, Lichen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965030/ https://www.ncbi.nlm.nih.gov/pubmed/35386446 http://dx.doi.org/10.1016/j.bioactmat.2022.01.026 |
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