CXCR4-guided liposomes regulating hypoxic and immunosuppressive microenvironment for sorafenib-resistant tumor treatment

Clinical sorafenib treatment could activate C-X-C receptor type 4 (CXCR4)/stromal source factor-1α (SDF-1α) axis to aggravate intra-tumoral hypoxia of hepatocellular carcinoma (HCC), which further leads to progression, invasion, metastasis, and immunosuppression of tumors and in return causes resist...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yuehua, Wang, Zhenjie, Jia, Fei, Xu, Qing, Shu, Zhilin, Deng, Junlin, Li, Aimin, Yu, Meng, Yu, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965090/
https://www.ncbi.nlm.nih.gov/pubmed/35386453
http://dx.doi.org/10.1016/j.bioactmat.2022.01.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965090/
https://www.ncbi.nlm.nih.gov/pubmed/35386453
http://dx.doi.org/10.1016/j.bioactmat.2022.01.003

Ejemplares similares