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SSH2.0: A Better Tool for Predicting the Hydrophobic Interaction Risk of Monoclonal Antibody

Therapeutic antibodies play a crucial role in the treatment of various diseases. However, the success rate of antibody drug development is low partially because of unfavourable biophysical properties of antibody drug candidates such as the high aggregation tendency, which is mainly driven by hydroph...

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Detalles Bibliográficos
Autores principales: Zhou, Yuwei, Xie, Shiyang, Yang, Yue, Jiang, Lixu, Liu, Siqi, Li, Wei, Abagna, Hamza Bukari, Ning, Lin, Huang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965096/
https://www.ncbi.nlm.nih.gov/pubmed/35368659
http://dx.doi.org/10.3389/fgene.2022.842127