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SSH2.0: A Better Tool for Predicting the Hydrophobic Interaction Risk of Monoclonal Antibody
Therapeutic antibodies play a crucial role in the treatment of various diseases. However, the success rate of antibody drug development is low partially because of unfavourable biophysical properties of antibody drug candidates such as the high aggregation tendency, which is mainly driven by hydroph...
Autores principales: | Zhou, Yuwei, Xie, Shiyang, Yang, Yue, Jiang, Lixu, Liu, Siqi, Li, Wei, Abagna, Hamza Bukari, Ning, Lin, Huang, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965096/ https://www.ncbi.nlm.nih.gov/pubmed/35368659 http://dx.doi.org/10.3389/fgene.2022.842127 |
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