PD-LI promotes rear retraction during persistent cell migration by altering integrin β4 dynamics

Although the immune checkpoint function of PD-L1 has dominated its study, we report that PD-L1 has an unanticipated intrinsic function in promoting the dynamics of persistent cell migration. PD-L1 concentrates at the rear of migrating carcinoma cells where it facilitates retraction, resulting in the...

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Detalles Bibliográficos
Autores principales: Wang, Mengdie, Xiong, Choua, Mercurio, Arthur M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965106/
https://www.ncbi.nlm.nih.gov/pubmed/35344032
http://dx.doi.org/10.1083/jcb.202108083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965106/
https://www.ncbi.nlm.nih.gov/pubmed/35344032
http://dx.doi.org/10.1083/jcb.202108083

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