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Copy number amplification-activated long non-coding RNA LINC00662 epigenetically inhibits BIK by interacting with EZH2 to regulate tumorigenesis in non-small cell lung cancer

Recently, studies have shown that lncRNAs play important roles in regulation of cancer cells proliferation, apoptosis and metastasis. Here, through systematic bioinformatics analysis and screening, we identified a long noncoding RNA LINC00662 with high copy number amplification in NSCLC. High expres...

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Detalles Bibliográficos
Autores principales: Yuan, Chunluan, Ding, Yue, Zhuang, Yan, Zhang, Chongguo, Han, Liang, Li, Wei, Guo, Renhua, Zhang, Erbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965125/
https://www.ncbi.nlm.nih.gov/pubmed/35371316
http://dx.doi.org/10.7150/jca.69210