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DDX21 Interacts with WDR5 to Promote Colorectal Cancer Cell Proliferation by Activating CDK1 Expression

DEAD-box RNA helicase 21 (DDX21), is a nucleolar protein harboring ATP-dependent double-stranded RNA unwinding activities, essential in rRNA processing and ribosome biogenesis. However, its role in colorectal cancer (CRC) progression remains unclear. In this study, we show that knockdown of DDX21 si...

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Detalles Bibliográficos
Autores principales: Lu, Peifen, Yu, Zenong, Wang, Kangning, Zhai, Yongping, Chen, Bing, Liu, Ming, Xu, Peipei, Li, Feng, Zhao, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965128/
https://www.ncbi.nlm.nih.gov/pubmed/35371306
http://dx.doi.org/10.7150/jca.69216