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Suppression of ATG4B by copper inhibits autophagy and involves in Mallory body formation

Autophagy is an evolutionarily conserved self-protecting mechanism implicated in cellular homeostasis. ATG4B plays a vital role in autophagy process via undertaking priming and delipidation of LC3. Chemical inhibitors and regulative modifications such as oxidation of ATG4B have been demonstrated to...

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Detalles Bibliográficos
Autores principales: Xia, Fan, Fu, Yuanyuan, Xie, Huazhong, Chen, Yuxin, Fang, Dongmei, Zhang, Wei, Liu, Peiqing, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965161/
https://www.ncbi.nlm.nih.gov/pubmed/35349929
http://dx.doi.org/10.1016/j.redox.2022.102284