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Suppression of ATG4B by copper inhibits autophagy and involves in Mallory body formation
Autophagy is an evolutionarily conserved self-protecting mechanism implicated in cellular homeostasis. ATG4B plays a vital role in autophagy process via undertaking priming and delipidation of LC3. Chemical inhibitors and regulative modifications such as oxidation of ATG4B have been demonstrated to...
Autores principales: | Xia, Fan, Fu, Yuanyuan, Xie, Huazhong, Chen, Yuxin, Fang, Dongmei, Zhang, Wei, Liu, Peiqing, Li, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965161/ https://www.ncbi.nlm.nih.gov/pubmed/35349929 http://dx.doi.org/10.1016/j.redox.2022.102284 |
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