Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats

BACKGROUND: Neutrophil elastase (NE) is associated with sepsis occurrence and progression. We hypothesized that the NE inhibitor Sivelestat might modulate abnormal gut microbiota and metabolites during sepsis. METHODS: Sixty Sprague-Dawley (SD) rats were randomly divided into sham control (SC), seps...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Sun, Yali, Ding, Xianfei, Cui, Yuqing, Li, Hongyi, Wang, Dong, Liang, Huoyan, Liu, Shaohua, Zhang, Xiaojuan, Wang, Haixu, Sun, Tongwen
Μορφή: Online Άρθρο Κείμενο
Γλώσσα:English
Έκδοση: Frontiers Media S.A. 2022
Θέματα:
Cellular and Infection Microbiology
Διαθέσιμο Online:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965314/
https://www.ncbi.nlm.nih.gov/pubmed/35372122
http://dx.doi.org/10.3389/fcimb.2022.818391

Διαδίκτυο

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965314/
https://www.ncbi.nlm.nih.gov/pubmed/35372122
http://dx.doi.org/10.3389/fcimb.2022.818391

Παρόμοια τεκμήρια