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Key Disease Mechanisms Linked to Amyotrophic Lateral Sclerosis in Spinal Cord Motor Neurons

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with no modifying treatments available. The molecular mechanisms underpinning disease pathogenesis are not fully understood. Recent studies have employed co-expression networks to identify key genes, known as “switch genes”, re...

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Detalles Bibliográficos
Autores principales: Bottero, Virginie, Santiago, Jose A., Quinn, James P., Potashkin, Judith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965442/
https://www.ncbi.nlm.nih.gov/pubmed/35370543
http://dx.doi.org/10.3389/fnmol.2022.825031