Structural Dissection of the First Events Following Membrane Binding of the Islet Amyloid Polypeptide

The islet amyloid polypeptide (IAPP) is the main constituent of the amyloid fibrils found in the pancreas of type 2 diabetes patients. The aggregation of IAPP is known to cause cell death, where the cell membrane plays a dual role: being a catalyst of IAPP aggregation and being the target of IAPP to...

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Detalles Bibliográficos
Autores principales: Khemtemourian, Lucie, Fatafta, Hebah, Davion, Benoit, Lecomte, Sophie, Castano, Sabine, Strodel, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965455/
https://www.ncbi.nlm.nih.gov/pubmed/35372496
http://dx.doi.org/10.3389/fmolb.2022.849979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965455/
https://www.ncbi.nlm.nih.gov/pubmed/35372496
http://dx.doi.org/10.3389/fmolb.2022.849979

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