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Disease-associated microglial activation prevents photoreceptor degeneration by suppressing the accumulation of cell debris and neutrophils in degenerating rat retinas

Retinitis pigmentosa initially presents as night blindness owing to defects in rods, and the secondary degeneration of cones ultimately leads to blindness. Previous studies have identified active roles of microglia in the pathogenesis of photoreceptor degeneration in RP. However, the contribution of...

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Detalles Bibliográficos
Autores principales: He, Juncai, Fu, Yan, Ge, Lingling, Dai, Jiaman, Fang, Yajie, Li, Yijian, Gu, Xianliang, Tao, Zui, Zou, Ting, Li, Minghui, Liu, Yong, Xu, Haiwei, Yin, Zheng Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965480/
https://www.ncbi.nlm.nih.gov/pubmed/35401812
http://dx.doi.org/10.7150/thno.67954