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The AlkB Family: Potential Prognostic Biomarkers and Therapeutic Targets in Glioblastoma
The AlkB family of Fe (II) and α-ketoglutarate-dependent dioxygenases works by removing alkyl substituents from alkylation-damaged nucleic acid bases through oxidative dealkylation, subsequently affecting tumor progression and patient prognosis. However, the specific roles of the AlkB family in Glio...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965608/ https://www.ncbi.nlm.nih.gov/pubmed/35371987 http://dx.doi.org/10.3389/fonc.2022.847821 |