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CAG Repeats Within the Non-pathological Range in the HTT Gene Influence Personality Traits in Patients With Subjective Cognitive Decline: A 13-Year Follow-Up Study

OBJECTIVE: HTT is a gene containing a key region of CAG repeats. When expanded beyond 39 repeats, Huntington disease (HD) develops. HTT genes with <35 repeats are not associated with HD. The biological function of CAG repeat expansion below the non-pathological threshold is not well understood. I...

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Detalles Bibliográficos
Autores principales: Moschini, Valentina, Mazzeo, Salvatore, Bagnoli, Silvia, Padiglioni, Sonia, Emiliani, Filippo, Giacomucci, Giulia, Morinelli, Carmen, Ingannato, Assunta, Freni, Tommaso, Belloni, Laura, Ferrari, Camilla, Sorbi, Sandro, Nacmias, Benedetta, Bessi, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965717/
https://www.ncbi.nlm.nih.gov/pubmed/35370826
http://dx.doi.org/10.3389/fpsyt.2022.826135