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CAG Repeats Within the Non-pathological Range in the HTT Gene Influence Personality Traits in Patients With Subjective Cognitive Decline: A 13-Year Follow-Up Study
OBJECTIVE: HTT is a gene containing a key region of CAG repeats. When expanded beyond 39 repeats, Huntington disease (HD) develops. HTT genes with <35 repeats are not associated with HD. The biological function of CAG repeat expansion below the non-pathological threshold is not well understood. I...
Autores principales: | Moschini, Valentina, Mazzeo, Salvatore, Bagnoli, Silvia, Padiglioni, Sonia, Emiliani, Filippo, Giacomucci, Giulia, Morinelli, Carmen, Ingannato, Assunta, Freni, Tommaso, Belloni, Laura, Ferrari, Camilla, Sorbi, Sandro, Nacmias, Benedetta, Bessi, Valentina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965717/ https://www.ncbi.nlm.nih.gov/pubmed/35370826 http://dx.doi.org/10.3389/fpsyt.2022.826135 |
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