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Polarization of tumor-associated macrophages by TLR7/8 conjugated radiosensitive peptide hydrogel for overcoming tumor radioresistance

Radioresistance reduces the antitumor efficiency of radiotherapy and further restricts its clinical application, which is mainly caused by the aggravation of immunosuppressive tumor microenvironment (ITM). Especially tumor-associated macrophages (TAMs) usually display the tumor-promoting M2 phenotyp...

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Detalles Bibliográficos
Autores principales: Zhang, Yumin, Feng, Zujian, Liu, Jinjian, Li, Hui, Su, Qi, Zhang, Jiamin, Huang, Pingsheng, Wang, Weiwei, Liu, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965723/
https://www.ncbi.nlm.nih.gov/pubmed/35386314
http://dx.doi.org/10.1016/j.bioactmat.2021.12.033