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Tissue Damage, Not Infection, Triggers Hepatic Unfolded Protein Response in an Experimental Rat Peritonitis Model

BACKGROUND: Abdominal surgery is an efficient treatment of intra-abdominal sepsis. Surgical trauma and peritoneal infection lead to the activation of multiple pathological pathways. The liver is particularly susceptible to injury under septic conditions. Liver function is impaired when pathological...

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Detalles Bibliográficos
Autores principales: Müllebner, Andrea, Herminghaus, Anna, Miller, Ingrid, Kames, Martina, Luís, Andreia, Picker, Olaf, Bauer, Inge, Kozlov, Andrey V., Duvigneau, Johanna Catharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965740/
https://www.ncbi.nlm.nih.gov/pubmed/35372445
http://dx.doi.org/10.3389/fmed.2022.785285