Autophagy Blockage Reduces the Incidence of Pancreatic Ductal Adenocarcinoma in the Context of Mutant Trp53

Macroautophagy (hereafter referred to as autophagy) is a homeostatic process that preserves cellular integrity. In mice, autophagy regulates pancreatic ductal adenocarcinoma (PDAC) development in a manner dependent on the status of the tumor suppressor gene Trp53. Studies published so far have inves...

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Detalles Bibliográficos
Autores principales: Mainz, Laura, Sarhan, Mohamed A. F. E., Roth, Sabine, Sauer, Ursula, Maurus, Katja, Hartmann, Elena M., Seibert, Helen-Desiree, Rosenwald, Andreas, Diefenbacher, Markus E., Rosenfeldt, Mathias T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965752/
https://www.ncbi.nlm.nih.gov/pubmed/35372352
http://dx.doi.org/10.3389/fcell.2022.785252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965752/
https://www.ncbi.nlm.nih.gov/pubmed/35372352
http://dx.doi.org/10.3389/fcell.2022.785252

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