Acute Myeloid Leukemia Cells Functionally Compromise Hematopoietic Stem/Progenitor Cells Inhibiting Normal Hematopoiesis Through the Release of Extracellular Vesicles

Acute myeloid leukemia (AML) is an aggressive and heterogeneous clonal disorder of hematopoietic stem/progenitor cells (HSPCs). It is not well known how leukemia cells alter hematopoiesis promoting tumor growth and leukemic niche formation. In this study, we investigated how AML deregulates the hema...

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Detalles Bibliográficos
Autores principales: Trino, Stefania, Laurenzana, Ilaria, Lamorte, Daniela, Calice, Giovanni, De Stradis, Angelo, Santodirocco, Michele, Sgambato, Alessandro, Caivano, Antonella, De Luca, Luciana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965808/
https://www.ncbi.nlm.nih.gov/pubmed/35371979
http://dx.doi.org/10.3389/fonc.2022.824562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965808/
https://www.ncbi.nlm.nih.gov/pubmed/35371979
http://dx.doi.org/10.3389/fonc.2022.824562

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