Cu(I) and Cu(II) Complexes Based on Lonidamine-Conjugated Ligands Designed to Promote Synergistic Antitumor Effects

[Image: see text] Bis(pyrazol-1-yl)- and bis(3,5-dimethylpyrazol-1-yl)-acetates were conjugated with the 2-hydroxyethylester and 2-aminoethylamide derivatives of the antineoplastic drug lonidamine to prepare Cu(I) and Cu(II) complexes that might act through synergistic mechanisms of action due to th...

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Detalles Bibliográficos
Autores principales: Del Bello, Fabio, Pellei, Maura, Bagnarelli, Luca, Santini, Carlo, Giorgioni, Gianfabio, Piergentili, Alessandro, Quaglia, Wilma, Battocchio, Chiara, Iucci, Giovanna, Schiesaro, Irene, Meneghini, Carlo, Venditti, Iole, Ramanan, Nitya, De Franco, Michele, Sgarbossa, Paolo, Marzano, Cristina, Gandin, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965879/
https://www.ncbi.nlm.nih.gov/pubmed/35285628
http://dx.doi.org/10.1021/acs.inorgchem.1c03658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965879/
https://www.ncbi.nlm.nih.gov/pubmed/35285628
http://dx.doi.org/10.1021/acs.inorgchem.1c03658

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