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Cu(I) and Cu(II) Complexes Based on Lonidamine-Conjugated Ligands Designed to Promote Synergistic Antitumor Effects
[Image: see text] Bis(pyrazol-1-yl)- and bis(3,5-dimethylpyrazol-1-yl)-acetates were conjugated with the 2-hydroxyethylester and 2-aminoethylamide derivatives of the antineoplastic drug lonidamine to prepare Cu(I) and Cu(II) complexes that might act through synergistic mechanisms of action due to th...
Autores principales: | Del Bello, Fabio, Pellei, Maura, Bagnarelli, Luca, Santini, Carlo, Giorgioni, Gianfabio, Piergentili, Alessandro, Quaglia, Wilma, Battocchio, Chiara, Iucci, Giovanna, Schiesaro, Irene, Meneghini, Carlo, Venditti, Iole, Ramanan, Nitya, De Franco, Michele, Sgarbossa, Paolo, Marzano, Cristina, Gandin, Valentina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965879/ https://www.ncbi.nlm.nih.gov/pubmed/35285628 http://dx.doi.org/10.1021/acs.inorgchem.1c03658 |
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