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Epigenetic Signatures Discriminate Patients With Primary Sclerosing Cholangitis and Ulcerative Colitis From Patients With Ulcerative Colitis

BACKGROUND: Primary sclerosing cholangitis (PSC) is a chronic inflammatory liver disease affecting the intra- and extrahepatic bile ducts, and is strongly associated with ulcerative colitis (UC). In this study, we explored the peripheral blood DNA methylome and its immune cell composition in patient...

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Detalles Bibliográficos
Autores principales: de Krijger, Manon, Hageman, Ishtu L., Li Yim, Andrew Y. F., Verhoeff, Jan, Garcia Vallejo, Juan J., van Hamersveld, Patricia H. P., Levin, Evgeni, Hakvoort, Theodorus B. M., Wildenberg, Manon E., Henneman, Peter, Ponsioen, Cyriel Y., de Jonge, Wouter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965896/
https://www.ncbi.nlm.nih.gov/pubmed/35371111
http://dx.doi.org/10.3389/fimmu.2022.840935